University of Northern Iowa
Posted in Transcriptomics on Mar 31st, 2008
Of the almost 25,000 human genes science that have been identified, half are believed to be silent at any particular time and activated only when needed.
Perhaps not, says Andre Ptitsyn, of the Center for Bioinfomatics at Colorado State University. He says he has discovered that current tools cannot measure extraordinarily low levels of gene [...]
Posted in Transcriptomics on Feb 15th, 2008
Research highlight by Frank C.P. Holstege, Department of Physiological Chemistry, University Medical Center Utrecht, the Netherlands.
For eukaryotes, it is widely thought that transcription is primarily regulated through recruitment of the essential machinery to transcription start-sites. Previous hints challenging this paradigm have been confirmed by recent analyses showing that transcription regulation of a large number of [...]
Posted in Transcriptomics on Jan 2nd, 2008
Cells keep a close watch over the transcriptome – the totality of all parts of the genome that are expressed in any given cell at any given time. Researchers at the Salk Institute for Biological Studies and the University of Missouri-Kansas City teamed up to peel back another layer of transcriptional regulation and gain new [...]